Disease Control of Inoperable HER2-Positive Breast Cancer by Targeted Molecular Drugs and Radiotherapy: A Case Report

Background: The number of elderly patients with breast cancer has increased in recent years, many whom reside alone. This makes choosing their treatment difficult because domestic considerations and declining physical cognitive functions. Chemotherapy is often omitted owing to age, can subsequently be inadequate. Case presentation: Our patient was an 82-year-old woman presenting the chief complaint enlarged left mass. mass had undergone self-destruction hemorrhage axillary supraclavicular lymph nodes. She lived alone; therefore, initial chemotherapy trastuzumab (HER)+pertuzumab (PER)+weekly paclitaxel (wPTX) two-step dose reduction performed hospital. A subcutaneous appeared, which disappeared after irradiation. Subsequently, tri-weekly HER+PER administration continued. Conclusion: multidisciplinary approach therapy may offer living alone inoperable ability continue control disease following careful consideration comorbidities decline Such options minimize occurrence side effects, allowing for long-term continuation therapy, helping maintain quality life potentially prolonging overall survival.